On the Presence of Nerves in Tumors and of Other Structures in Them as Revealed by a Modification of Ehrlich's Method of "vital Staining" with Methylene Blue

Our knowledge of neoplasms, notwithstanding the enormous amount of research to which they have been subjected, is still extremely vague and unsatisfactory. With nearly every advance in histological technique, however, its application to tumors has afforded some additional fact or facts concerning them, and it is only by utilizing for their study the various improvements of older methods or entirely novel procedures, that we may hope for the accumulation of data from which maybe deduced a satisfactory explanation of their origin and somatic relations. About a year ago, at the suggestion of Dr. Lewellys F. Barker of the Anatomical Laboratory, I undertook the study of some of the tumors obtainable in the surgical operating room of the Johns ttopldns Hospital, with Golgi's silver-method and with a modification of the method of vital staining by methylene-blue introduced by Ehrlich* of Ber l in . I have to thank Dr. Barker for instruction in the use of